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A2biotherapeutics
A radical new way to treat solid tumors. Powerful & precise T cell therapy that attacks solid tumors while sparing normal cells
About A2biotherapeutics
A2 Bio is a groundbreaking biotechnology startup that is revolutionizing the treatment of solid tumors through its proprietary Tmod™ platform. The company's primary focus is on developing innovative treatments for solid tumors, a type of cancer that begins in the solid organs such as the lungs, colon, or breast.
The Tmod™ platform is a powerful and precise T cell therapy that targets and attacks tumor cells while sparing normal cells. This is achieved by integrating multiple signals and exploiting specific gene losses that are only found in tumor cells, thereby overcoming the limitations of conventional single-target therapies.
A2 Bio's business model is centered on the development and commercialization of its Tmod™ platform. The company generates revenue through the clinical trials and eventual sale of its innovative cell therapies. A2 Bio's market is primarily patients suffering from solid tumors, including colorectal, pancreatic, and non-small cell lung cancers.
The company has a first-mover advantage in exploiting the loss of genetic material in cancer cells, a unique approach that sets it apart in the competitive biotech industry. A2 Bio is led by a seasoned management team with over 90 years of combined experience in cell therapy and biotechnology.
Recently, A2 Bio has made significant strides in its research and development efforts. In 2023, the company announced the first patient dosed in a Phase 1 clinical trial of A2B530, a novel cell therapy for the treatment of colorectal, pancreatic, and non-small cell lung cancers.
Source: Dealroom company dataAt a glance
- Status
- Operational
- Founded
- 2018
- Headquarters
- Agoura Hills, United States
- Employees
- 118
- Open positions
- 1
- Dealroom signal
- 66.6/100
- Industry
- Health
- Sub-industry
- Pharmaceutical, BioTechnology
- Sector
- Biotech & Life Sciences, Biotechnology, Oncology, Biotech and Pharma, DT and LS, science-based
- Business model
- Manufacturing
- Client focus
- b2b
Knowledge graph
More headlines
Funding history
Company financing events and reported valuations.
| Deal type | Date | Amount | Valuation | Investors | Source |
|---|---|---|---|---|---|
| SERIES COther financing | May 2025 | $80M | $320M | The Column Group · Samsara BioCapital | ↗ |
| SERIES COther financing | Jan 2025 | $80M | $320M | The Column Group · Samsara BioCapital | ↗ |
Growth signals
Latest recorded traffic for A2biotherapeutics is 5.4K monthly website visits, down 20.6% over the last three months. A2biotherapeutics's team declined 4.8% over the past year.
Similar companies
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Investments and acquisitions
Recent portfolio relationships for companies that also act as investors or acquirers.
Investors
From Dealroom's funding and investor records, grouped by the round each investor first entered.
Seed1 investor entered at this stage
Vida Ventures
Series A1 investor entered at this stage
Nextech Invest
Series B and later2 investors entered at this stage
The Column Group
Samsara BioCapital
Source: Dealroom Talent Intelligence.
Global footprint
team presence
Market sentiment
An AI-synthesised read of the highest-engagement posts about A2biotherapeutics on X, ranked by likes and reposts, corporate channels excluded.
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Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour
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