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1E Therapeutics

Biotech & Life Sciences · Rehovot, Israel · Founded 2020

Focuses on developing oligonucleotide therapeutics to treat various diseases MoreLess

1E Therapeutics, operating under the domain 1etx.com, is a pioneering pharmaceutical startup that is revolutionizing the future of therapeutic treatments. The company's primary focus is on the development of a new class of drugs, known as programmable oligonucleotide therapeutics. These are essentially small pieces of DNA or RNA that can be programmed to target and silence disease-causing RNAs in human or pathogen cells. In simpler terms, these drugs are designed to stop the production of harmful proteins that cause diseases.

The company's innovative approach has the potential to treat a wide range of diseases that have been historically difficult to manage, including genetically driven diseases like cancer, ALS, Huntington’s disease, Angelman syndrome, and multidrug-resistant bacteria like MRSA and Pseudomonas. They also aim to address central nervous system disorders, age-related disorders, and metabolic diseases.

1E Therapeutics operates in the biotechnology and pharmaceutical market, serving a broad range of clients including hospitals, healthcare providers, and patients suffering from the aforementioned diseases. Their business model revolves around the research, development, and commercialization of their programmable oligonucleotide therapeutics. The company generates revenue through the sale of these innovative drugs once they have been approved for use in the market.

Keywords: 1E Therapeutics, programmable oligonucleotide therapeutics, disease-causing RNAs, genetically driven diseases, multidrug-resistant bacteria, central nervous system disorders, age-related disorders, metabolic diseases, biotechnology, pharmaceutical market.

Company overview

1E Therapeutics company information

The essential company record, classifications and operating signals in one place.

Status
Operational
Founded
2020
Headquarters
Rehovot, Israel
Employees
47
Open positions
1
Dealroom signal
69.4
client focusb2bsub industryPharmaceuticalsub industryBioTechnologybusiness modelManufacturingindustryHealthsectorBiotechnologysectorGenetics and genomicssectorRNAsectorDiseasesectorBiotech and PharmasectorHard TechsectorDT and LSsectorscience-based

Valuation & funding

1E Therapeutics funding history

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
SEEDOther financing Dec 2021 $120M $480M Marius Nacht
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Growth signals

1E Therapeutics website traffic

Latest recorded traffic for 1E Therapeutics is 170 monthly website visits, down 41.4% over the last three months. 1E Therapeutics's team declined 2.1% over the past year.

Latest monthly visits170 3-month web change-41.4% 1-year team growth-2.1%
Monthly website visits14 observations · Nov 2022–Jun 2024
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Hiring

Open positions at 1E Therapeutics

Current openings linked to this company in Dealroom.

2 distinct openings shownExplore hiring signals →

Comparisons

1E Therapeutics compared with similar companies

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Talent graph

1E Therapeutics's talent

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Team profiled 3 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 2 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Investors

1 investor on 1E Therapeutics's cap table

Sourced from Dealroom's funding and investor records.

Seed 1 investor entered at this stage
Marius Nacht

Global footprint

Where 1E Therapeutics has talent and traffic

Workforce by country
2 countries with
team presence
🇮🇱 Israel94.9%
🇺🇸 United States2.6%
2 countries shown

In the news

Latest news about 1E Therapeutics

Recent press, funding announcements, and product moves mentioning 1E Therapeutics — open to read from the original sources.

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Market sentiment

What the market is saying about 1E Therapeutics

An AI-synthesized read of the highest-engagement posts about 1E Therapeutics on X over the past 7 days. We rank by likes & retweets, ignore corporate channels, and surface the themes that broke out from real people.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

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