Product Reports Resources Pricing Login Book a demo
COMPANY PROFILE

1E Therapeutics

Explore full profile

Focuses on developing oligonucleotide therapeutics to treat various diseases

Rehovot, IsraelFounded 2020Biotech & Life Sciences
Valuation $500M–1B Last recorded · 2021
Headcount <100 Current team size
Total funding $100–500M Disclosed equity funding
Unlock exact values This page shows ranges. Dealroom has the exact numbers for 1E Therapeutics and the history behind them.

About 1E Therapeutics

1E Therapeutics, operating under the domain 1etx.com, is a pioneering pharmaceutical startup that is revolutionizing the future of therapeutic treatments. The company's primary focus is on the development of a new class of drugs, known as programmable oligonucleotide therapeutics. These are essentially small pieces of DNA or RNA that can be programmed to target and silence disease-causing RNAs in human or pathogen cells. In simpler terms, these drugs are designed to stop the production of harmful proteins that cause diseases.

The company's innovative approach has the potential to treat a wide range of diseases that have been historically difficult to manage, including genetically driven diseases like cancer, ALS, Huntington’s disease, Angelman syndrome, and multidrug-resistant bacteria like MRSA and Pseudomonas. They also aim to address central nervous system disorders, age-related disorders, and metabolic diseases.

1E Therapeutics operates in the biotechnology and pharmaceutical market, serving a broad range of clients including hospitals, healthcare providers, and patients suffering from the aforementioned diseases. Their business model revolves around the research, development, and commercialization of their programmable oligonucleotide therapeutics. The company generates revenue through the sale of these innovative drugs once they have been approved for use in the market.

Source: Dealroom company data

At a glance

Status
Operational
Founded
2020
Headquarters
Rehovot, Israel
Employees
47
Open positions
1
Dealroom signal
69.4/100
Industry
Health
Sub-industry
Pharmaceutical, BioTechnology
Sector
Biotech & Life Sciences, Biotechnology, Genetics and genomics, RNA, Disease, Biotech and Pharma, Hard Tech, DT and LS, science-based
Business model
Manufacturing
Client focus
b2b

Funding history

1 recorded event

Company financing events and reported valuations.

Deal typeDateAmountValuationInvestorsSource
SEEDOther financing Dec 2021 $120M $480M Marius Nacht ↗
Showing the latest 1 of 1 recorded eventsBook a demo for the full funding history →

Growth signals

1E Therapeutics website traffic

Latest recorded traffic for 1E Therapeutics is 170 monthly website visits, down 41.4% over the last three months. 1E Therapeutics's team declined 2.1% over the past year.

Latest monthly visits170 3-month web change-41.4% 1-year team growth-2.1%
Summary metrics are public; monthly history is available with a demoCompare with peers →

Investments and acquisitions

Capital deployed

Recent portfolio relationships for companies that also act as investors or acquirers.

Investors

1 investor on the cap table

From Dealroom's funding and investor records, grouped by the round each investor first entered.

Seed1 investor entered at this stage

  • Marius Nacht
Team profiled 3 named & role-tagged
Founders Hidden — book a demo/100 quality score
Key operators 2 quality Hidden — book a demo/100
Potential founders Hidden — book a demo likely future founders
Startup mafia Hidden — book a demo alumni-founded startups
Talent movements Hidden — book a demo in · Hidden — book a demo out past 12 months

Source: Dealroom Talent Intelligence.

Global footprint

Workforce and web traffic by country
Workforce by country
2 countries with
team presence
🇮🇱 Israel94.9%
🇺🇸 United States2.6%
2 countries shown

Market sentiment

Posts on X, past 7 days

An AI-synthesised read of the highest-engagement posts about 1E Therapeutics on X, ranked by likes and reposts, corporate channels excluded.

Reading the room on X — pulling top posts and synthesizing themes…

Source: X recent search ranked by engagement (likes + retweets) · Synthesis by Claude · Cached for 1 hour

See 1E Therapeutics’s full profile on Dealroom

Request a free trial to see the complete deal history, financials, people graph and growth signals.

Takes under a minute. Already use Dealroom? Log in.