US Novel AI Startups
63 US startups pushing the AI frontier — foundational and world models, novel algorithms and applications, physical and engineering AI including autonomous driving, and efficient, trustworthy AI. Combined funding $425B across 31 unicorns.
Foundational models
Anthropic OpenAI Adept xAI Reka AI Nous Research
World models
World Labs Luma AI Odyssey Fundamental Archetype AI Symbolica Decart
Novel AI algorithms
Safe Superintelligence Liquid AI Thinking Machines Lab humans& Flapping Airplanes Elorian Axiom Math Engramme CTGT Harmonic Goodfire Cartesia
Applications with advanced proprietary models
Perplexity Runway Sesame Reflection AI Aaru Hedra Gracia AI Cartwheel Higgsfield Cognition | Devin AI Poolside AI Magic
Autonomous driving
Waymo Applied Intuition Stack AV Pony.ai Avride Aurora Helm.ai Nuro May Mobility
AI CADs and algorithms
InfinitForm Navier AI Arena Physica
TinyML
webAI Clipto OpenInfer
Privacy-enhancing technologies (PETs)
Sahara Opaque Systems
Dealroom.co