Synthetic biology (SynBio) is revolutionizing how we engineer life, merging biology with AI, automation, and molecular design to create groundbreaking solutions in healthcare, sustainability, and manufacturing. By redesigning genetic systems and developing programmable organisms (often microbes and bacteria), startups in this space are pushing the boundaries of medicine, biofuels, biomaterials, and food & agritech innovation.  This mapping showcases 500+ leading startups pioneering synthetic biology across application areas.